Herbal diuretic weight loss
Obese: Use ideal body weight for dosing calculations. Common side effects include nausea, stomach pain, loss of appetite, poor coordination, increased hair growth, and enlargement of the gums. Focal seizures: Mainly used to protect against the development of focal seizures with complex symptomatology (psychomotor and temporal lobe seizures). Chronic phenytoin use has been associated with decreased bone density and increased bone fractures. Folate is presented in foods as polyglutamate, which is then converted into monoglutamates by intestinal conjugase. Tonic-clonic seizures: Mainly used in the prophylactic management of tonic-clonic seizures with complex symptomatology (psychomotor seizures). Avoid giving intramuscular formulation unless necessary due to skin cell death and local tissue destruction. Phenytoin may accumulate in the cerebral cortex over long periods of time which can cause atrophy of the cerebellum. However, can be used in combination with other anticonvulsants during combined absence and tonic-clonic seizures. Phenytoin may increase risk of suicidal thoughts or behavior. Effects consist of the following: bleeding upon probing, increased gingival exudate, pronounced gingival inflammatory response to plaque levels, associated in some instances with bone loss but without tooth detachment. Absence seizures: Not used in treatment of pure absence seizures due to risk for increasing frequency of seizures. Digoxin toxicity: IV formulation is drug of choice for arrhythmias caused by cardiac glycoside toxicity. The intravenous form is used for status epilepticus that does not improve with benzodiazepines. This leads to increased metabolism of vitamin D, thus decreased vitamin D levels. It may also be used for certain heart arrhythmias or neuropathic pain. At therapeutic doses, phenytoin may produce nystagmus on lateral gaze. There is evidence that use during pregnancy results in abnormalities in the baby. Seizures during surgery: Used as prevention and treatment of seizures occurring during and after neurosurgery. Potentially serious side effects include sleepiness, self harm, liver problems, bone marrow suppression, low blood pressure, and toxic epidermal necrolysis.
Phenytoin is primarily metabolized to its inactive form by the enzyme CYP2C9. IV use is contraindicated in patients with sinus bradycardia, SA block, second- or third-degree AV block, Stokes-Adams syndrome, or have known hypersensitivity to phenytoin or any ingredient in the respective formulation or to other hydantoins. Kidney disease: Do not use oral loading dose. Common side effects include nausea, stomach pain, loss of appetite, poor coordination, increased hair growth, and enlargement of the gums. Pregnancy: Pregnancy Category D due to risk of fetal hydantoin syndrome and fetal bleeding. Liver disease: Do not use oral loading dose. However, optimal seizure control is very important during pregnancy so drug may be continued if benefits outweigh the risks. There is evidence that use during pregnancy results in abnormalities in the baby. Due to decreased drug concentrations during pregnancy, dose of phenytoin may need to be increased if only option for seizure control. It appears to be safe to use when breastfeeding. Heart monitoring should occur during and after IV infusion. It is useful for the prevention of tonic-clonic seizures, partial seizures, but not absence seizures. Potentially serious side effects include sleepiness, self harm, liver problems, bone marrow suppression, low blood pressure, and toxic epidermal necrolysis. Severe low blood pressure and abnormal heart rhythms can be seen with rapid infusion of IV phenytoin. Can begin with standard maintenance dose and adjust as needed. Abnormal heart rhythms: may be used in the treatment of ventricular tachycardia and sudden episodes of atrial tachycardia after other antiarrhythmic medications or cardioversion has failed. Also effective in controlling partial seizures with autonomic symptoms. Hypertrichosis, Stevens-Johnson syndrome, purple glove syndrome, rash, exfoliative dermatitis, itching, excessive hairiness, and coarsening of facial features can be seen in those taking phenytoin. It has been suggested that phenytoin causes a reduction in folic acid levels, predisposing patients to megaloblastic anemia. Herbal diuretic weight loss video:
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